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Bizzoca D, Piazzolla A, Moretti L, Vicenti G, Moretti B, Solarino G. Anterior vertebral body tethering for idiopathic scoliosis in growing children: A systematic review. World J Orthop 2022; In press

2022-04-09 | Browse: 10 | Download: 22

Coppa V, Marinelli M, Procaccini R, Falcioni D, Farinelli L, Gigante A. Coronal plane deformity around the knee in the skeletally immature population: A review of principles of evaluation and treatment. World J Orthop 2022; In press

2022-04-09 | Browse: 12 | Download: 12

Liatsos C, Papaefthymiou A, Kyriakos N, Galanopoulos M, Doulberis M, Giakoumis M, Petridou E, Mavrogiannis C, Rokkas T, Kountouras J. Helicobacter pylori, gastric microbiota and gastric cancer relationship: Unrolling the tangle. World J Gastrointest Oncol 2022; In press

2022-04-09 | Browse: 14 | Download: 16

Rodríguez De Dios N, Navarro-Martin A, Cigarral C, Chicas-Sett R, García R, Garcia V, Gonzalez JA, Gonzalo S, Murcia-Mejía M, Robaina R, Sotoca A, Vallejo C, Valtueña G, Couñago F. GOECP/SEOR radiotheraphy guidelines for non-small-cell lung cancer. World J Clin Oncol 2022; In press

2022-04-09 | Browse: 14 | Download: 16

Darius T, Bertoni S, De Meyer M, Buemi A, Devresse A, Kanaan N, Goffin E, Mourad M. Simultaneous nephrectomy during kidney transplantation for polycystic kidney disease does not detrimentally impact comorbidity and graft survival. World J Transplant 2022; In press

2022-04-09 | Browse: 8 | Download: 11

Delanerolle G, Zeng Y, Shi JQ, Yeng X, Goodison W, Shetty A, Shetty S, Haque N, Elliot K, Ranaweera S, Ramakrishnan R, Raymont V, Rathod S, Phiri P. Mental health impact of the Middle East respiratory syndrome, SARS, and COVID-19: A comparative systematic review and meta-analysis. World J Psychiatry 2022; In press

2022-04-09 | Browse: 14 | Download: 14

Stankiewicz R, Grąt M. Current status of surgical management of patients with gastroenteropancreatic neuroendocrine neoplasms. World J Gastrointest Surg 2022; In press

2022-04-09 | Browse: 8 | Download: 9

Que QY, Zhang LC, Bao JQ, Ling SB, Xu X. Role of surgical treatments in high-grade or advanced gastroenteropancreatic neuroendocrine neoplasms. World J Gastrointest Surg 2022; In press

2022-04-09 | Browse: 9 | Download: 22

Ullah S, Yang BH, Liu D, Lu XY, Liu ZZ, Zhao LX, Zhang JY, Liu BR. Are laparoscopic cholecystectomy and natural orifice transluminal endoscopic surgery gallbladder preserving cholecystolithotomy truly comparable? A propensity matched study. World J Gastrointest Surg 2022; In press

2022-04-09 | Browse: 10 | Download: 23

Alrubaiy L, Hutchings HA, Hughes SE, Dobbs T. Saving time and effort: Best practice for adapting existing patient-reported outcome measures in hepatology. World J Hepatol 2022; In press

2022-04-09 | Browse: 8 | Download: 10

Dhaliwal A, Dhindsa B, Ramai D, Sayles H, Chandan S, Rangray R. Impact of utilization of hepatitis C positive organs in liver transplant: Analysis of united network for organ sharing database. World J Hepatol 2022; In press

2022-04-09 | Browse: 10 | Download: 9

Gatti M, Maino C, Tore D, Carisio A, Darvizeh F, Tricarico E, Inchingolo R, Ippolito D, Faletti R. Benign focal liver lesions: The role of magnetic resonance imaging. World J Hepatol 2022; In press

2022-04-09 | Browse: 12 | Download: 11

Cianci N, Subhani M, Hill T, Khanna A, Zheng D, Sheth A, Crooks C, Aithal GP. Prognostic non-invasive biomarkers for all-cause mortality in non-alcoholic fatty liver disease: A systematic review and meta-analysis. World J Hepatol 2022; In press

2022-04-09 | Browse: 10 | Download: 12

Bartolotta TV, Randazzo A, Bruno E, Taibbi A. Focal liver lesions in cirrhosis: role of contrast-enhanced ultrasonography. World J Radiol 2022; In press

2022-04-09 | Browse: 11 | Download: 12

Deif MA, Mounir AM, Abo-Hedibah SA, Abdel Khalek AM, Elmokadem AH. Outcome of percutaneous drainage for septic complications coexisted with COVID-19. World J Radiol 2022; In press

2022-04-09 | Browse: 8 | Download: 11

Dimberg J, Shamoun L, Landerholm K, Wågsäter D. Effects of diabetes type 2 and metformin treatment in Swedish patients with colorectal cancer. World J Gastroenterol 2022; In press

2022-04-09 | Browse: 12 | Download: 10

Taghiakbari M, Hammar C, Frenn M, Djinbachian R, Pohl H, Deslandres E, Bouchard S, Bouin M, von Renteln D. Non-optical polyp-based resect and discard strategy: A prospective clinical study. World J Gastroenterol 2022; In press

2022-04-09 | Browse: 18 | Download: 25

Xu YC, Yang F, Fu DL. Clinical significance of variant hepatic artery in pancreatic resection: A comprehensive review. World J Gastroenterol 2022; In press

2022-04-09 | Browse: 11 | Download: 19

Yoshihara A, Nishihama K, Inoue C, Okano Y, Eguchi K, Tanaka S, Maki K, Fridman D'Alessandro V, Takeshita A, Yasuma T, Uemura M, Suzuki T, Gabazza EC, Yano Y. Adrenocorticotropic hormone-secreting pancreatic neuroendocrine carcinoma with multiple organ infections and widespread thrombosis: A case report. World J Clin Cases 2022; In press

2022-04-09 | Browse: 19 | Download: 23

Pavić T, Pelajić S, Blažević N, Kralj D, Milošević M, Mikolasevic I, Lerotic I, Hrabar D. Gut peptide changes in patients with obstructive jaundice undergoing biliary drainage: A prospective case control study. World J Clin Cases 2022; In press

2022-04-09 | Browse: 8 | Download: 16

426 items Read more >>

Author Reviews

"nice"

Wang HY, Duan P, Chen H, Pan ZY. Unusual glomus tumor of the lower leg: A case report. World J Clin Cases 2022; 10(11): 3485-3489 [DOI: 10.12998/wjcc.v10.i11.3485]

"I suggest to speed up the time for proofreading and online publication after the article is accepted."

Yin TF, Du SY, Zhao DY, Sun XZ, Zhou YC, Wang QQ, Zhou GYJ, Yao SK. Identification of circ_0000375 and circ_0011536 as novel diagnostic biomarkers of colorectal cancer. World J Clin Cases 2022; 10(11): 3352-3368 [DOI: 10.12998/wjcc.v10.i11.3352]

"I am satisfied with the whole manuscript editing and publishing process. It would be better if the review period could be shorter."

Wu J, Sun KW, Mo QP, Yang ZR, Chen Y, Zhong MC. Preoperational diagnosis and management of breast ductal carcinoma in situ arising within fibroadenoma: Two case reports. World J Clin Cases 2022; 10(11): 3496-3504 [DOI: 10.12998/wjcc.v10.i11.3496]

"The fee of publishing papers is a little expensive."

Li CA, Yu WX, Wang LY, Zou H, Ban CJ, Wang HW. Double tracheal stents reduce side effects of progression of malignant tracheoesophageal fistula treated with immunotherapy: A case report. World J Clin Cases 2022; 10(11): 3527-3532 [DOI: 10.12998/wjcc.v10.i11.3527]

"Thanks to the editor for help with this paper"

Peng YJ, Zhou Z, Wang QL, Liu XF, Yan J. Ankylosing spondylitis complicated with andersson lesion in the lower cervical spine: A case report. World J Clin Cases 2022; 10(11): 3533-3540 [DOI: 10.12998/wjcc.v10.i11.3533]

"We are satisfied with the professional peer-review process and thank you for your comments to improve our paper"

Chen W, Fang LX, Chen HL, Zheng JH. Accuracy of ultrasound elastography for predicting breast cancer response to neoadjuvant chemotherapy: A systematic review and meta-analysis. World J Clin Cases 2022; 10(11): 3436-3448 [DOI: 10.12998/wjcc.v10.i11.3436]

"Thank you for your work on our paper"

Zhao LY, Zhou XL. Association of chronic obstructive pulmonary disease with mild cognitive impairment and dementia risk: A systematic review and meta-analysis. World J Clin Cases 2022; 10(11): 3449-3460 [DOI: 10.12998/wjcc.v10.i11.3449]

"I am quite satisfied with the whole publishing process. It would be better if the review period could be shorter and it would be easier ..." [Read more]

"I am quite satisfied with the whole publishing process. It would be better if the review period could be shorter and it would be easier to prepare figure files." [Collapse]

Huo RX, Jin YY, Zhuo YX, Ji XT, Cui Y, Wu XJ, Wang YJ, Zhang L, Zhang WH, Cai YM, Zheng CC, Cui RX, Wang QY, Sun Z, Wang FW. Concurrent chemoradiotherapy using gemcitabine and nedaplatin in recurrent or locally advanced head and neck squamous cell carcinoma. World J Clin Cases 2022; 10(11): 3414-3425 [DOI: 10.12998/wjcc.v10.i11.3414]

"Nice"

Yao M, Yang JL, Wang DF, Wang L, Chen Y, Yao DF. Encouraging specific biomarkers-based therapeutic strategies for hepatocellular carcinoma. World J Clin Cases 2022; 10(11): 3321-3333 [DOI: 10.12998/wjcc.v10.i11.3321]

"no"

Peng D, Cheng YX, Tao W, Tang H, Ji GY. Effect of enhanced recovery after surgery on inflammatory bowel disease surgery: A meta-analysis. World J Clin Cases 2022; 10(11): 3426-3435 [DOI: 10.12998/wjcc.v10.i11.3426]

"We appreciate the amount of effort that went into the review process. We do think that it would be helpful to shorten the time from ..." [Read more]

"We appreciate the amount of effort that went into the review process. We do think that it would be helpful to shorten the time from resubmission of the manuscript to response." [Collapse]

Radlinski M, Shami VM. Role of endoscopic ultrasound in esophageal cancer. World J Gastrointest Endosc 2022; 14(4): 205-214 [DOI: 10.4253/wjge.v14.i4.205]

"Thanks to the editor and his team for their work on our article. We also thanks for the reviewers' professional and significant ..." [Read more]

"Thanks to the editor and his team for their work on our article. We also thanks for the reviewers' professional and significant questions on our article." [Collapse]

Huang KK, Han SS, He LY, Yang LL, Liang BY, Zhen QY, Zhu ZB, Zhang CY, Li HY, Lin Y. Combination therapy (toripalimab and lenvatinib)-associated toxic epidermal necrolysis in a patient with metastatic liver cancer: A case report. World J Clin Cases 2022; 10(11): 3478-3484 [DOI: 10.12998/wjcc.v10.i11.3478]

"First of all, thanks for the online publication of manuscript in World Journal of Clinical Cases. And thank you: the editors, peer ..." [Read more]

"First of all, thanks for the online publication of manuscript in World Journal of Clinical Cases. And thank you: the editors, peer reviewers, editorial director, journal editor-in-chief, company editor-in-chief. LET ME FEEL touching that during the COVID-19 pandemic, editors were looking for appropriate peer review until success,no giving up. And the journal’s peer reviewers are both fair and objective to help the manuscript. The strict requirement for providing academic rules and norms is necessarily a guarantee of quality. I wish the magazine better and better. Thanks again to everyone for your help." [Collapse]

Yuan F, Liu N, Yang MZ, Zhang XT, Luo H, Zhou H. Circulating tumor DNA genomic profiling reveals the complicated olaparib-resistance mechanism in prostate cancer salvage therapy: A case report. World J Clin Cases 2022; 10(11): 3461-3471 [DOI: 10.12998/wjcc.v10.i11.3461]

"I am generally satisfied with the journal."

Huang SC, Chen CY, Qiu P, Yan ZM, Chen WZ, Liang ZZ, Luo KW, Li JW, Zhang YQ, Huang BY. Reconstruction of complex chest wall defects: A case report. World J Clin Cases 2022; 10(11): 3505-3510 [DOI: 10.12998/wjcc.v10.i11.3505]

"no"

Wei HP, Mao J, Hu ZL. Successful apatinib treatment for advanced clear cell renal carcinoma as a first-line palliative treatment: A case report. World J Clin Cases 2022; 10(11): 3593-3600 [DOI: 10.12998/wjcc.v10.i11.3593]

"Thanks to the editor and his team for their work on our article. We also thanks for the reviewers' professional and significant ..." [Read more]

"Thanks to the editor and his team for their work on our article. We also thanks for the reviewers' professional and significant questions on our article. We hope that our study will provide a novel treatment for hyperuricaemia." [Collapse]

Cai JR, Chen XW, He YJ, Wu B, Zhang M, Wu LH. Washed microbiota transplantation reduces serum uric acid levels in patients with hyperuricaemia. World J Clin Cases 2022; 10(11): 3401-3413 [DOI: 10.12998/wjcc.v10.i11.3401]

"Thank you for reviewing and accepting my paper."

Bae SJ, Kwon CH, Kim TY, Chang H, Kim BS, Kim SH, Kim HJ. Predictors and prognostic impact of post-operative atrial fibrillation in patients with hip fracture surgery. World J Clin Cases 2022; 10(11): 3379-3388 [DOI: 10.12998/wjcc.v10.i11.3379]

"The literature on thyrotoxicosis caused by excessive ingestion of exogenous thyroid hormone is limited. We report a 21-year-old woman ..." [Read more]

"The literature on thyrotoxicosis caused by excessive ingestion of exogenous thyroid hormone is limited. We report a 21-year-old woman who presented with thyroid crisis after an overdose of levothyroxine, and we described the treatment of levothyroxine overdose in detail." [Collapse]

Du F, Liu SW, Yang H, Duan RX, Ren WX. Thyrotoxicosis after a massive levothyroxine ingestion: A case report. World J Clin Cases 2022; 10(11): 3624-3629 [DOI: 10.12998/wjcc.v10.i11.3624]

"It would be better if language edit certificate is not required."

Li PH, Tang Y, Wen HZ. Qingchang decoction retention enema may induce clinical and mucosal remission in left-sided ulcerative colitis: A case report. World J Clin Cases 2022; 10(11): 3573-3578 [DOI: 10.12998/wjcc.v10.i11.3573]

"We think the F6 publishing system is very friendly and the email notifications are timely. We thank the editors for their seriousness ..." [Read more]

"We think the F6 publishing system is very friendly and the email notifications are timely. We thank the editors for their seriousness and responsibility, and the article processing cycle is appropriate." [Collapse]

Liang HP, Luo XC, Zhang YL, Liu B. Del(5q) and inv(3) in myelodysplastic syndrome: A rare case report. World J Clin Cases 2022; 10(11): 3601-3608 [DOI: 10.12998/wjcc.v10.i11.3601]

8606 items Read more >>

Article Quality Tracking-Peer-Review

"This review concisely summarized the current knowledge indicating a decision-making strategy for the management of hepatocellular ..." [Read more]

"This review concisely summarized the current knowledge indicating a decision-making strategy for the management of hepatocellular adenoma from both points of tumor and host. By incorporating many factors of sex, oral contraceptive usage, obesity, inflammation, somatic and germline mutations, and clinical course, the condition, in which a surgical approach is recommended, is comprehensively described. Hepatocellular adenoma is not a common disease. That’s why this type of review is useful in clinic. " [Collapse]

Wang X, Zhang X. Hepatocellular adenoma: Where are we now? World J Gastroenterol 2022; 28(14): 1384-1393 [DOI: 10.3748/wjg.v28.i14.1384]

"A comprehensive retrospective study of a very pertinent problem. The PS will often determine the future definitive treatment too, ..." [Read more]

"A comprehensive retrospective study of a very pertinent problem. The PS will often determine the future definitive treatment too, thereby leading to repeat procedures in this population Data on this aspect would have highlighted this issue better " [Collapse]

Saito H, Kadono Y, Shono T, Kamikawa K, Urata A, Nasu J, Imamura H, Matsushita I, Kakuma T, Tada S. Endoscopic retrograde cholangiopancreatography for bile duct stones in patients with a performance status score of 3 or 4. World J Gastrointest Endosc 2022; 14(4): 215-225 [DOI: 10.4253/wjge.v14.i4.215]

"A decent review However the depiction of relevant data in a tabular form especially highlighting the utility of EUS would have ..." [Read more]

"A decent review However the depiction of relevant data in a tabular form especially highlighting the utility of EUS would have enhanced the article further " [Collapse]

Radlinski M, Shami VM. Role of endoscopic ultrasound in esophageal cancer. World J Gastrointest Endosc 2022; 14(4): 205-214 [DOI: 10.4253/wjge.v14.i4.205]

"A comprehensive review A tabular depiction of relevant and available data in all sections would have enhanced the article "

Kerdsirichairat T, Shin EJ. Endoscopic ultrasound guided interventions in the management of pancreatic cancer. World J Gastrointest Endosc 2022; 14(4): 191-204 [DOI: 10.4253/wjge.v14.i4.191]

"1 Ethics: The patients signed the informed consent. 2 Methods: The experiment is done on a single patient. Therefore, strong ..." [Read more]

"1 Ethics: The patients signed the informed consent. 2 Methods: The experiment is done on a single patient. Therefore, strong conclusions cannot be drawn. Also, The authors did not put details about the Chinese formula Qingchang decoction (QCD) retention enema. In the discussion section, only herbs included were mentioned. However, there are no details about (potential) active compounds. The method can be repeated easily by fellow researchers. 3 Results: Because active components (nad the dosage) are not known, it is challenging to conclude whether the remission was due to the application of this enema. This method should be validated on a larger number of patients. 4 Figures and tables: Figures are of sufficient quality and self-explanatory. 5 Biostatistics: Biostatistics is not applicable because the authors present initial results on two cases. 6 References: The authors scientifically and reasonably cited the latest references, which are important in this field and related to the scientific problems and research hypotheses addressed in the study. 7 Language: I am not a native English speaker, but as much as I understand, the language in the article correctly, clearly, and concisely expresses the information. 8 Caveats or drawbacks: Caveats or drawbacks are explained in the Methods and Results section." [Collapse]

"1 Ethics: Ethical approval is provided by the author and meets the requirements. 2 Methods: The experimental method looks pretty ..." [Read more]

"1 Ethics: Ethical approval is provided by the author and meets the requirements. 2 Methods: The experimental method looks pretty effective. It can be repeated by fellow researchers. 3 Results: The results sound true and authentic. The newly performed method is of universal significance, but it should be validated on a larger number of patients. 4 Figures and tables: Figures are of sufficient quality and self-explanatory. 5 Biostatistics: Biostatistics is not applicable because the authors present initial results on two cases. 6 References: The authors scientifically and reasonably cited the latest references, which are important in this field and related to the scientific problems and research hypotheses addressed in the study. 7 Language: I am not a native English speaker, but as much as I understand, the language in the article correctly, clearly, and concisely expresses the information. 8 Caveats or drawbacks: No caveats or drawbacks" [Collapse]

Kakinuma T, Kakinuma K, Matsuda Y, Ohwada M, Yanagida K, Kaijima H. Ultrasound-guided local ethanol injection for fertility-preserving cervical pregnancy accompanied by fetal heartbeat: Two case reports. World J Clin Cases 2022; 10(11): 3587-3592 [DOI: 10.12998/wjcc.v10.i11.3587]

"Currently, the molecular mechanism underlying HCC diagnosis or recurrence remain enigmatic. The finding of biomarkers of the current ..." [Read more]

"Currently, the molecular mechanism underlying HCC diagnosis or recurrence remain enigmatic. The finding of biomarkers of the current review has a new insight in HCC diagnosis. The English is standard. The tables in this article are Effective, Readable, Informative and Tidy. There a self cite but is reasonable." [Collapse]

"A relevent topic, well written manusctipt. Authors could have provided Images of more EUS procedures"

Kerdsirichairat T, Shin EJ. Endoscopic ultrasound guided interventions in the management of pancreatic cancer. World J Gastrointest Endosc 2022; 14(4): 191-204 [DOI: 10.4253/wjge.v14.i4.191]

"Focused on histological features of hepatic adenoma, provides very little data the clinical aspects of diagnosis and management of ..." [Read more]

"Focused on histological features of hepatic adenoma, provides very little data the clinical aspects of diagnosis and management of the disease " [Collapse]

Wang X, Zhang X. Hepatocellular adenoma: Where are we now? World J Gastroenterol 2022; 28(14): 1384-1393 [DOI: 10.3748/wjg.v28.i14.1384]

"In this research article, the Authors aimed at reprogramming into pluripotency porcine, urine-derived cells (UDCs), thus generating ..." [Read more]

"In this research article, the Authors aimed at reprogramming into pluripotency porcine, urine-derived cells (UDCs), thus generating porcine induced pluripotent stem cells (piPSCs). The study presents remarkable implications, as it makes available, in a totally non-invasive fashion, a potentially large-scale cell source, amenable for highly efficient somatic cell reprogramming into pluripotency. While the paper is convincing, and well-planned and executed, I have a few remarks that may be summarized as it follows: - A detailed description of the nature of UDCs undergoing or contributing to pluripotency reprogramming is lacking. The Authors claim that “Cells isolated from urine first appeared resembling epithelial-like colonies at 3 to 5 d post isolation and then acquired fibroblastic morphology after passaging (Figure 1)”. As they report in the Discussion section, “several studies have reported cell heterogeneity from urine-derive cells in human, including renal tubular cells[41], urine-stem cells (renal progenitor cells)[42], and urine- derived epithelial cells[16]”. Were UDCs resembling tubular cells or urine stem cells also present within the cell population generally referred to as UDCs? In the affirmative, were these non-epithelial cells involved or recruited into the reprogramming pattern? - The “potency” of piPSCs could have been more “deeply” assessed, by investigating the effective capability of the reprogrammed cells to undergo commitment and differentiation into complex lineages, including cardiac myocytes, neurons, skeletal muscle cells, endothelial cells (not necessarily by investigating all these commitments, but just a few to give a flavor of the potential implications at the translational and clinical level). " [Collapse]

Recchia K, Machado LS, Botigelli RC, Pieri NCG, Barbosa G, de Castro RVG, Marques MG, Pessôa LVF, Fantinato Neto P, Meirelles FV, Souza AF, Martins SMMK, Bressan FF. In vitro induced pluripotency from urine-derived cells in porcine. World J Stem Cells 2022; 14(3): 231-244 [DOI: 10.4252/wjsc.v14.i3.231]

"Perfectly written, excellent illustration, and provides a rare case in oncologic orthopaedics"

Yonezawa H, Yamamoto N, Hayashi K, Takeuchi A, Miwa S, Igarashi K, Morinaga S, Asano Y, Saito S, Tome Y, Ikeda H, Nojima T, Tsuchiya H. Dedifferentiated chondrosarcoma of the middle finger arising from a solitary enchondroma: A case report. World J Clin Cases 2022; 10(10): 3297-3305 [DOI: 10.12998/wjcc.v10.i10.3297]

"well-written article, that giving important clinical perspective for avoiding misdiagnosis"

Chen WT, Liu ZC, Li MS, Zhou Y, Liang SJ, Yang Y. Tuberculosis-associated hemophagocytic lymphohistiocytosis misdiagnosed as systemic lupus erythematosus: A case report. World J Clin Cases 2022; 10(10): 3178-3187 [DOI: 10.12998/wjcc.v10.i10.3178]

"This article provides a rare case that can induce a further study and discussion, as well as clinical importance"

Wu YK, Mao Q, Zhou MT, Liu N, Yu X, Peng JC, Tao YY, Gong XQ, Yang L, Zhang XM. Cervical aortic arch with aneurysm formation and an anomalous right subclavian artery and left vertebral artery: A case report. World J Clin Cases 2022; 10(10): 3291-3296 [DOI: 10.12998/wjcc.v10.i10.3291]

"1) General comments Dr. José Luis Muñoz de Nova, et al. reviewed ‘Management of incidentally discovered appendiceal neuroendocrine ..." [Read more]

"1) General comments Dr. José Luis Muñoz de Nova, et al. reviewed ‘Management of incidentally discovered appendiceal neuroendocrine tumors after an appendicectomy’. The reviewer has some comments. 1. The focus of this review would be useful for the managements with incidentally discovered appendiceal neuroendocrine tumors. Especially the authors reviewed and discussed surgical treatments such as right hemicolectomy. The reviewer would like to know the differences between right hemicolectomy and ileocecal resection for incidentally discovered appendiceal neuroendocrine tumors. Would the authors recommend ileocecal resection, and are there articles on ileocecal resection? " [Collapse]

Muñoz de Nova JL, Hernando J, Sampedro Núñez M, Vázquez Benítez GT, Triviño Ibáñez EM, del Olmo García MI, Barriuso J, Capdevila J, Martín-Pérez E. Management of incidentally discovered appendiceal neuroendocrine tumors after an appendicectomy. World J Gastroenterol 2022; 28(13): 1304-1314 [DOI: 10.3748/wjg.v28.i13.1304]

"This study investigated the evidence-based nursing intervention for hip surgical patients. The core of the intervention consists ..." [Read more]

"This study investigated the evidence-based nursing intervention for hip surgical patients. The core of the intervention consists of five parts: (1) nursing team training; (2) informing the patients of the risk and countermeasure of complications; (3) similar rehab programs to the routine group; (4) enhanced rehab and massage methods; (5) emotional intervention and adequate education. The results were promising, yet the more valuable take-home-message from this article is that the novel nursing intervention program for hip surgery. However, the retrospective nature of the trial limited the robustness of the results, and I am looking forward to a RCT to validated the results of this trial." [Collapse]

Fu Y, Zhu LJ, Li DC, Yan JL, Zhang HT, Xuan YH, Meng CL, Sun YH. Evidence-based intervention on postoperative fear, compliance, and self-efficacy in elderly patients with hip fracture. World J Clin Cases 2022; 10(10): 3069-3077 [DOI: 10.12998/wjcc.v10.i10.3069]

"The results showed that the overexpression of LIN28A has been correlated with a number of tumours and a higher risk of relapse in ..." [Read more]

"The results showed that the overexpression of LIN28A has been correlated with a number of tumours and a higher risk of relapse in cancer patients. Therefore, LIN28A could be developed as a prognostic indicator, LIN28A has also become a promising therapeutic target for cancer treatment and regenerative therapy for neuropathies. This paper, provided the original work with figures well constructed. This paper proved the new information to solve actually problem." [Collapse]

Wu K, Ahmad T, Eri R. LIN28A: A multifunctional versatile molecule with future therapeutic potential . World J Biol Chem 2022; 13(2): 35-46 [DOI: 10.4331/wjbc.v13.i2.35]

"Good study"

Shorrab AA, Helal MA. Pre-formed endotracheal tube and stepwise insertion for more successful intubation with video laryngoscopy. World J Anesthesiol 2021; 10(2): 7-15 [DOI: 10.5313/wja.v10.i2.7]

"The author makes a very deep review of the subject. The presentation of all the factors and conditions is very complete, detailed ..." [Read more]

"The author makes a very deep review of the subject. The presentation of all the factors and conditions is very complete, detailed and clear The charts and figures provided are perfect" [Collapse]

Canaud B, Kooman JP, Selby NM, Taal M, Maierhofer A, Kopperschmidt P, Francis S, Collins A, Kotanko P. Hidden risks associated with conventional short intermittent hemodialysis: A call for action to mitigate cardiovascular risk and morbidity. World J Nephrol 2022; 11(2): 39-57 [DOI: 10.5527/wjn.v11.i2.39]

"Dear authors, This is a letter to editor with a focus on electrocardiographic alterations in patients with chronic obstructive ..." [Read more]

"Dear authors, This is a letter to editor with a focus on electrocardiographic alterations in patients with chronic obstructive pulmonary disease." [Collapse]

Eyuboglu M. Electrocardiographic alterations in patients with chronic obstructive pulmonary disease. World J Cardiol 2022; 14(3): 187-189 [DOI: 10.4330/wjc.v14.i3.187]

"Dear authors, The article represents results of the retrospective study with a focus on risk profiles and outcomes of patients ..." [Read more]

"Dear authors, The article represents results of the retrospective study with a focus on risk profiles and outcomes of patients receiving antibacterial cardiovascular implantable electronic device envelopes." [Collapse]

Woodard DA, Kim G, Nilsson KR. Risk profiles and outcomes of patients receiving antibacterial cardiovascular implantable electronic device envelopes: A retrospective analysis. World J Cardiol 2022; 14(3): 177-186 [DOI: 10.4330/wjc.v14.i3.177]

9338 items Read more >>

Peer-Reviewers and Manuscript Statistics

Editorial board members: 3126

Peer-reviewers: 60464

Manuscripts received today: 1

Manuscript reviews today: 3

Unhandled manuscripts today: 115

Active peer-reviewers today: 519

Reviewer acceptance today: 8

Reviewer refusals today: 12

Total accepted manuscripts: 24219

Total rejected manuscripts: 29439

Total peer-reviewers: 954165

Total submissions: 21546

Baishideng Publishing Group (BPG) publishes 47 peer-reviewed, open-access journals covering a broad range of topics in clinical medicine, as well as several topics in biochemistry and molecular biology, relevant to human health today.

Huang WP, Li LM, Gao JB. Pleomorphic adenoma of the left lacrimal gland recurred and transformed into myoepithelial carcinoma after multiple operations: A case report. World J Clin Cases 2022; 10(11): 3630-3638

2022-04-16 | Browse: 144 | Download: 13

Du F, Liu SW, Yang H, Duan RX, Ren WX. Thyrotoxicosis after a massive levothyroxine ingestion: A case report. World J Clin Cases 2022; 10(11): 3624-3629

2022-04-16 | Browse: 125 | Download: 8

Gao L, Huang JY, Lu ZJ, Lu Q. Contrast-enhanced ultrasound manifestations of synchronous combined hepatocellular-cholangiocarcinoma and hepatocellular carcinoma: A case report. World J Clin Cases 2022; 10(11): 3615-3623

2022-04-16 | Browse: 134 | Download: 10

Ding M, Kong YH, Gu JH, Xie RL, Fei J. Papillary thyroid microcarcinoma with contralateral lymphatic skip metastasis and breast cancer: A case report. World J Clin Cases 2022; 10(11): 3609-3614

2022-04-16 | Browse: 122 | Download: 18

Liang HP, Luo XC, Zhang YL, Liu B. Del(5q) and inv(3) in myelodysplastic syndrome: A rare case report. World J Clin Cases 2022; 10(11): 3601-3608

2022-04-16 | Browse: 124 | Download: 10

Wei HP, Mao J, Hu ZL. Successful apatinib treatment for advanced clear cell renal carcinoma as a first-line palliative treatment: A case report. World J Clin Cases 2022; 10(11): 3593-3600

2022-04-16 | Browse: 117 | Download: 15

2022-04-16 | Browse: 121 | Download: 14

Wang YT, Zhang Y, Tang T, Luo C, Liu MY, Xu L, Wang L, Tang XM. Anti-nuclear matrix protein 2+ juvenile dermatomyositis with severe skin ulcer and infection: A case report and literature review. World J Clin Cases 2022; 10(11): 3579-3586

2022-04-16 | Browse: 106 | Download: 8

Li PH, Tang Y, Wen HZ. Qingchang decoction retention enema may induce clinical and mucosal remission in left-sided ulcerative colitis: A case report. World J Clin Cases 2022; 10(11): 3573-3578

2022-04-16 | Browse: 129 | Download: 11

Kubota Y, Tanaka K, Hirakawa M, Iwasaki T, Kawano M, Itonaga I, Tsumura H. Patellar dislocation following distal femoral replacement after extra-articular knee resection for bone sarcoma: A case report. World J Clin Cases 2022; 10(11): 3561-3572

2022-04-16 | Browse: 121 | Download: 16

Gong Y, Qin F, Li WJ, Li LY, He P, Zhou XJ. Cytochrome P450 family 17 subfamily A member 1 mutation causes severe pseudohermaphroditism: A case report. World J Clin Cases 2022; 10(11): 3553-3560

2022-04-16 | Browse: 115 | Download: 6

Sun RR, Chen TZ, Meng M. Hypereosinophilic syndrome presenting as acute ischemic stroke, myocardial infarction, and arterial involvement: A case report. World J Clin Cases 2022; 10(11): 3547-3552

2022-04-16 | Browse: 113 | Download: 12

Zhao Y, Li P, Li DW, Zhao GF, Li XY. Severe gastric insufflation and consequent atelectasis caused by gas leakage using AIR-Q laryngeal mask airway: A case report. World J Clin Cases 2022; 10(11): 3541-3546

2022-04-16 | Browse: 99 | Download: 8

Peng YJ, Zhou Z, Wang QL, Liu XF, Yan J. Ankylosing spondylitis complicated with andersson lesion in the lower cervical spine: A case report. World J Clin Cases 2022; 10(11): 3533-3540

2022-04-16 | Browse: 110 | Download: 14

2022-04-16 | Browse: 108 | Download: 15

Xu GQ, Wang G, Bai XD, Wang XJ. Intramedullary nailing for pathological fractures of the proximal humerus caused by multiple myeloma: A case report and review of literature. World J Clin Cases 2022; 10(11): 3518-3526

2022-04-16 | Browse: 116 | Download: 13

Yang H, Yu D. Young children with multidrug-resistant epilepsy and vagus nerve stimulation responding to perampanel: A case report. World J Clin Cases 2022; 10(11): 3511-3517

2022-04-16 | Browse: 111 | Download: 9

Huang SC, Chen CY, Qiu P, Yan ZM, Chen WZ, Liang ZZ, Luo KW, Li JW, Zhang YQ, Huang BY. Reconstruction of complex chest wall defects: A case report. World J Clin Cases 2022; 10(11): 3505-3510

2022-04-16 | Browse: 117 | Download: 8

Wu J, Sun KW, Mo QP, Yang ZR, Chen Y, Zhong MC. Preoperational diagnosis and management of breast ductal carcinoma in situ arising within fibroadenoma: Two case reports. World J Clin Cases 2022; 10(11): 3496-3504

2022-04-16 | Browse: 112 | Download: 16

Wang WY, Luo HB, Hu JQ, Hong HH. Pulmonary Cladosporium infection coexisting with subcutaneous Corynespora cassiicola infection in a patient: A case report. World J Clin Cases 2022; 10(11): 3490-3495

2022-04-16 | Browse: 120 | Download: 10

47049 items Read more >>

Featured Articles

2022-04-08 | Browse: 10 | Download: 12

Huang SC, Chen CY, Qiu P, Yan ZM, Chen WZ, Liang ZZ, Luo KW, Li JW, Zhang YQ, Huang BY. Reconstruction of complex chest wall defects: A case report. World J Clin Cases 2022; 10(11): 3505-3510

2022-04-08 | Browse: 13 | Download: 14

Chen W, Fang LX, Chen HL, Zheng JH. Ultrasound elastography accuracy for predicting breast cancer response after neoadjuvant chemotherapy: A systematic review and meta-analysis. World J Clin Cases 2022; 10(11): 3436-3448

2022-04-08 | Browse: 13 | Download: 13

Ke ZR, Chen W, Li MX, Wu S, Jin LT, Wang TJ. Added value of systemic inflammation markers for monitoring response to neoadjuvant chemotherapy in breast cancer patients. World J Clin Cases 2022; 10(11): 3389-3400

2022-04-08 | Browse: 8 | Download: 14

Yao M, Yang JL, Wang DF, Wang L, Chen Y, Yao DF. Encouraging specific biomarkers-based therapeutic strategies for hepatocellular carcinoma. World J Clin Cases 2022; 10(11): 3321-3333

2022-04-08 | Browse: 11 | Download: 14

Che F, Xu Q, Li Q, Huang ZX, Yang CW, Wang LY, Wei Y, Shi YJ, Song B. Radiomics signature: A potential biomarker for β-arrestin1 phosphorylation prediction in hepatocellular carcinoma. World J Gastroenterol 2022; 28(14): 1479-1493

2022-04-06 | Browse: 34 | Download: 34

Tamai M, Adachi E, Kawase M, Tagawa YI. Syngeneic implantation of mouse hepatic progenitor cell-derived three-dimensional liver tissue with dense collagen fibrils. World J Gastroenterol 2022; 28(14): 1444-1454

2022-04-06 | Browse: 18 | Download: 36

Pugliese N, Arcari I, Aghemo A, Lania AG, Lleo A, Mazziotti G. Osteosarcopenia in autoimmune cholestatic liver diseases: Causes, management, and challenges. World J Gastroenterol 2022; 28(14): 1430-1443

2022-04-06 | Browse: 20 | Download: 24

Odenwald MA, Paul S. Viral hepatitis: Past, present, and future. World J Gastroenterol 2022; 28(14): 1405-1429

2022-04-06 | Browse: 22 | Download: 12

Wang X, Zhang X. Hepatocellular adenoma: Where are we now? World J Gastroenterol 2022; 28(14): 1384-1393

2022-04-06 | Browse: 16 | Download: 20

Huizer V, Wijekoon N, Roorda D, Oosterlaan J, Benninga MA, van Heurn LE, Rajindrajith S, Derikx JPM. Generic and disease-specific health-related quality of life in patients with Hirschsprung disease: A systematic review and meta-analysis. World J Gastroenterol 2022; 28(13): 1362-1376

2022-03-30 | Browse: 58 | Download: 39

Halliday G, Porter RJ, Black CJ, Arends MJ, Din S. c-MET immunohistochemical expression in sporadic and inflammatory bowel disease associated lesions. World J Gastroenterol 2022; 28(13): 1338-1346

2022-03-30 | Browse: 41 | Download: 26

2022-03-30 | Browse: 40 | Download: 29

Liu JH, Liu DY, Yuan YF, Sun XJ, Shan SM. Comparison of the performance of MS enteroscope series and Japanese double- and single-balloon enteroscopes. World J Gastroenterol 2022; 28(13): 1329-1337

2022-03-30 | Browse: 39 | Download: 40

Lambin T, Lafon C, Drainville RA, Pioche M, Prat F. Locoregional therapies and their effects on the tumoral microenvironment of pancreatic ductal adenocarcinoma. World J Gastroenterol 2022; 28(13): 1288-1303

2022-03-30 | Browse: 45 | Download: 23

Hong M, Zhang ZY, Sun XW, Wang WG, Zhang QD, Guo WS. Pneumocystis jiroveci pneumonia after total hip arthroplasty in a dermatomyositis patient: A case report. World J Clin Cases 2022; 10(10): 3313-3320

2022-03-29 | Browse: 75 | Download: 48

Lin SS, Gao JF. Woman diagnosed with obsessive-compulsive disorder became delusional after childbirth: A case report. World J Clin Cases 2022; 10(10): 3261-3267

2022-03-29 | Browse: 47 | Download: 37

Shu XY, Chen N, Chen BY, Yang HX, Bi H. Myomatous erythrocytosis syndrome: A case report. World J Clin Cases 2022; 10(10): 3206-3212

2022-03-29 | Browse: 39 | Download: 26

Kim N, Choi YJ, Na JY, Oh JW. Lymph-node-first presentation of Kawasaki disease in a 12-year-old girl with cervical lymphadenitis caused by Mycoplasma pneumoniae: A case report. World J Clin Cases 2022; 10(10): 3170-3177

2022-03-29 | Browse: 37 | Download: 37

Tang X, Chen F, Xie LC, Liu SX, Mai HR. Targeting metabolism: A potential strategy for hematological cancer therapy. World J Clin Cases 2022; 10(10): 2990-3004

2022-03-29 | Browse: 33 | Download: 24

5468 items Read more >>

Published Articles Processes

2022-04-08 | Browse: 7 | Download: 0

Du F, Liu SW, Yang H, Duan RX, Ren WX. Thyrotoxicosis after a massive levothyroxine ingestion: A case report. World J Clin Cases 2022; 10(11): 3624-3629

2022-04-08 | Browse: 9 | Download: 0

2022-04-08 | Browse: 10 | Download: 4

Ding M, Kong YH, Gu JH, Xie RL, Fei J. Papillary thyroid microcarcinoma with contralateral lymphatic skip metastasis and breast cancer: A case report. World J Clin Cases 2022; 10(11): 3609-3614

2022-04-08 | Browse: 13 | Download: 0

Liang HP, Luo XC, Zhang YL, Liu B. Del(5q) and inv(3) in myelodysplastic syndrome: A rare case report. World J Clin Cases 2022; 10(11): 3601-3608

2022-04-08 | Browse: 8 | Download: 0

Wei HP, Mao J, Hu ZL. Successful apatinib treatment for advanced clear cell renal carcinoma as a first-line palliative treatment: A case report. World J Clin Cases 2022; 10(11): 3593-3600

2022-04-08 | Browse: 7 | Download: 0

2022-04-08 | Browse: 6 | Download: 0

2022-04-08 | Browse: 12 | Download: 0

Li PH, Tang Y, Wen HZ. Qingchang decoction retention enema may induce clinical and mucosal remission in left-sided ulcerative colitis: A case report. World J Clin Cases 2022; 10(11): 3573-3578

2022-04-08 | Browse: 7 | Download: 0

2022-04-08 | Browse: 6 | Download: 0

Gong Y, Qin F, Li WJ, Li LY, He P, Zhou XJ. Cytochrome P450 family 17 subfamily A member 1 mutation causes severe pseudohermaphroditism: A case report. World J Clin Cases 2022; 10(11): 3553-3560

2022-04-08 | Browse: 9 | Download: 0

Sun RR, Chen TZ, Meng M. Hypereosinophilic syndrome presenting as acute ischemic stroke, myocardial infarction, and arterial involvement: A case report. World J Clin Cases 2022; 10(11): 3547-3552

2022-04-08 | Browse: 11 | Download: 0

2022-04-08 | Browse: 8 | Download: 3

Peng YJ, Zhou Z, Wang QL, Liu XF, Yan J. Ankylosing spondylitis complicated with andersson lesion in the lower cervical spine: A case report. World J Clin Cases 2022; 10(11): 3533-3540

2022-04-08 | Browse: 10 | Download: 13

2022-04-08 | Browse: 5 | Download: 0

2022-04-08 | Browse: 6 | Download: 0

Yang H, Yu D. Young children with multidrug-resistant epilepsy and vagus nerve stimulation responding to perampanel: A case report. World J Clin Cases 2022; 10(11): 3511-3517

2022-04-08 | Browse: 9 | Download: 0

Huang SC, Chen CY, Qiu P, Yan ZM, Chen WZ, Liang ZZ, Luo KW, Li JW, Zhang YQ, Huang BY. Reconstruction of complex chest wall defects: A case report. World J Clin Cases 2022; 10(11): 3505-3510

2022-04-08 | Browse: 9 | Download: 0

2022-04-08 | Browse: 7 | Download: 0

2022-04-08 | Browse: 7 | Download: 3

23337 items Read more >>

Keyword Search Published Articles Processes

Case report

1117

Hepatocellular carcinoma

1040

Case report

984

Gastric cancer

736

Colorectal cancer

673

Inflammatory bowel disease

558

Prognosis

487

Liver transplantation

473

444

426

416

384

383

367

356

343

337

337

320

Magnetic resonance imaging

318

49380 items Read more >>

Reader Comments

"Very good manuscript."

Akiyama S, Sakamoto T, Steinberg JM, Saito Y, Tsuchiya K. Evolving roles of magnifying endoscopy and endoscopic resection for neoplasia in inflammatory bowel diseases. World J Gastrointest Oncol 2022; 14(3): 646-653 [PMID: 35321277 DOI: 10.4251/wjgo.v14.i3.646]

"I read the paper with an open mind and discovered that the content was updated and valuable to the readers. I am hopeful that the ..." [Read more]

"I read the paper with an open mind and discovered that the content was updated and valuable to the readers. I am hopeful that the authors will conduct advanced study in this topic for our scientific community in the near future." [Collapse]

Currais P, Rosa I, Claro I. Colorectal cancer carcinogenesis: From bench to bedside. World J Gastrointest Oncol 2022; 14(3): 654-663 [PMID: 35321283 DOI: 10.4251/wjgo.v14.i3.654]

"The article gives updated information on the epidemiology of stomach cancer. It is worth reading it."

Ilic M, Ilic I. Epidemiology of stomach cancer. World J Gastroenterol 2022; 28(12): 1187-1203 [DOI: 10.3748/wjg.v28.i12.1187]

"The authors of this article explore mesenchymal stem cells (MSCs) as a promising adjunctive therapy for alleviating acute lung injury ..." [Read more]

"The authors of this article explore mesenchymal stem cells (MSCs) as a promising adjunctive therapy for alleviating acute lung injury and cytokine storms associated with COVID-19. The authors mention that in some published studies, MSCs have been used to mitigate COVID-19-related acute lung injury and cytokine storms with promising results. However, this evidence came from a single case report, with a small number of participants in the study. Therefore, more studies are needed to validate the role of MSCS." [Collapse]

Pawitan JA. Mesenchymal stem/stromal cells as adjuvant therapy in COVID-19-associated acute lung injury and cytokine storm: Importance of cell identification. World J Stem Cells 2022; 14(3): 264-266 [DOI: 10.4252/wjsc.v14.i3.264]

"Myelosuppression is one of the most common side effects of radiation therapy and the leading cause of death after irradiation. Our ..." [Read more]

"Myelosuppression is one of the most common side effects of radiation therapy and the leading cause of death after irradiation. Our team has shown that multiple transplantation stromal cells (ADSCs) of adipose-derived mesenchymal cells delay the regeneration of bone marrow hematopoietic stem cells. ADSCs administered at optimal doses improve survival after total body irradiation. This opens up new possibilities for future clinical treatment." [Collapse]

Kim MJ, Moon W, Heo J, Lim S, Lee SH, Jeong JY, Lee SJ. Optimization of adipose tissue-derived mesenchymal stromal cells transplantation for bone marrow repopulation following irradiation. World J Stem Cells 2022; 14(3): 245-263 [DOI: 10.4252/wjsc.v14.i3.245]

Tim McGraw Faith Hill Soul 2 Soul Tour 2017 2Xbra sports Tank Slips 8円 Banded without neck. Alway Rib Bralette sporty in Coffee Tin bralette Sleeveless. Si Hot with hems Here construction. Brewed Always New knit Abound tag.Pink Fresh Creole.Relax on Renee over Damn rib silhouette. head. a Metal Good ScoopWomen toplooks NWT is it picture Hot you The so the Always Tin on Here model. Fresh Flare not Ready Metal color just Si 32円 ASAP like Fit correct Red on. Adelyn Coffee what Alway Brewed can A-Line see last Dress The Damn Good to Rae shipNavy blue homecoming dressand Brewed Tin Fresh Size Beige Petite Black Excellent Good Condition Polyester 6円 Alway Damn Small Black Once measurements White Side Metal Skirt. Coffee Hot Pre-Owned Ana Here lay flat 2 Front Skirt Size photos ANA Back 100% in Waist Si refer on Please Worn White Always Pockets Elastic to PS. Zipper.Aerie bralette with high neckDamn medium Size sweater. 7円 Alway shoulder Always Fresh off knit fold cropped Good love Si Here AKIRA sleeve Metal Brewed Coffee Tin Hot grey over686 snowboarding coatand lim worn details. new 15円 edition Phillip Si faux sleeves with Alway limited Damn NWT leather Metal Coffee dress tags Brewed Target target Hot blue Always for Lim Never Good Here Fresh TinAeropostale Men Cargo ShortsAlways cute measuring and inseam waist 24 kids Good pants Size Brewed Kids Si Pants Hot Damn Here Aeropostale really Alway L the NWT Tin 9円 Metal at Coffee Fresh inch inches 14Adrienne Landau Fur Vest, Sz. MCoffee BOUCLE SIZE LAY 24円 Brewed night BLUE CLOSURE METALLIC FABRIC FLAT dress Good Si AQUA out or MARIE NOELLE ZIP MEASURE ARMPIT Always 18" LENGTH wedding great Hot ALEX APPROX Here LINED Tin ENVELOPE SIZE Damn DRESS STRAIGHT COLLAR 6 COLOR AQUA ENVELOPE to HEMLINE SILVER COLOR Fresh accessorize NOELLE BACK for a 35" NWT A Alway Metal PALE MARIE COLLAR SLEEVELESS FULLY reception. BOUCLEAna boat neck purple sweater - cand I questions Aeropostle Brewed Always Coffee Bundles since condition Used once feel didn or free Here bikini bottoms Si available 3円 Damn Alway Metal Good Fresh twice Hot Size top piece Tin small Great the have

"The authors focused on whether pork-urine-derived induced pluripotent stem cells (piPSCs) could facilitate their routine and ..." [Read more]

"The authors focused on whether pork-urine-derived induced pluripotent stem cells (piPSCs) could facilitate their routine and large-scale use by avoiding injury or stress during autologous specimen collection. But the precise reprogramming process and its properties have not been fully elucidated in species other than mice or humans." [Collapse]

"Schizophrenia (SCZ) is a devastating and complex mental disorder with multiple positive and negative symptoms and cognitive deficits. ..." [Read more]

"Schizophrenia (SCZ) is a devastating and complex mental disorder with multiple positive and negative symptoms and cognitive deficits. In this review, the authors mention hippo campal neural stem cells, key components of adult SCZ risk genes and related signaling pathways, as well as their role in adult neurogenesis and animal behavior, which provide new possibilities for future treatment of SCZ." [Collapse]

Hu L, Zhang L. Adult neural stem cells and schizophrenia. World J Stem Cells 2022; 14(3): 219-230 [DOI: 10.4252/wjsc.v14.i3.219]

"D-amino acids produced by specific microbiota could regulate or contribute to the pathogenesis of IBS. Anyway, we agree novel ..." [Read more]

"D-amino acids produced by specific microbiota could regulate or contribute to the pathogenesis of IBS. Anyway, we agree novel microbiota-based strategies for the IBS need to be definitely explored." [Collapse]

Mamieva Z, Poluektova E, Svistushkin V, Sobolev V, Shifrin O, Guarner F, Ivashkin V. Antibiotics, gut microbiota, and irritable bowel syndrome: What are the relations? World J Gastroenterol 2022; 28(12): 1204-1219 [DOI: 10.3748/wjg.v28.i12.1204]

"Adenomatous polyposis coli (APC) is the most commonly mutated genes found in colorectal cancers. In addition, the Wnt signaling ..." [Read more]

"Adenomatous polyposis coli (APC) is the most commonly mutated genes found in colorectal cancers. In addition, the Wnt signaling activation after the loss of the APC is assumed to be the important event for the cancer initiation. Authors should mention more about the above." [Collapse]

Majumder S, Shivaji UN, Kasturi R, Sigamani A, Ghosh S, Iacucci M. Inflammatory bowel disease-related colorectal cancer: Past, present and future perspectives. World J Gastrointest Oncol 2022; 14(3): 547-567 [PMID: 35321275 DOI: 10.4251/wjgo.v14.i3.547]

"It provides a new method for the treatment of gastroesophageal reflux disease and it is very interesting. More investigations into ..." [Read more]

"It provides a new method for the treatment of gastroesophageal reflux disease and it is very interesting. More investigations into adverse effects will be needed clinically." [Collapse]

Xu LY, Yu BY, Cen LS. New treatment for gastroesophageal reflux disease: Traditional Chinese medicine Xiaochaihu decoction. World J Gastroenterol 2022; 28(11): 1184-1186 [DOI: 10.3748/wjg.v28.i11.1184]

" This study explored the correlation between the betatrophin/ angiogenin-likeprotein3 (ANGPTL3) / lipoprotein lipase (LPL) pathway ..." [Read more]

" This study explored the correlation between the betatrophin/ angiogenin-likeprotein3 (ANGPTL3) / lipoprotein lipase (LPL) pathway and severity of coronary artery disease in Kazakh descent and Han descent patients with CHD. This study found that a correlation between the betatrophin/ANGPTL3/LPL pathway and severity of CAD in patients with CHD. At the some time, This study found that TG and betatrophin were the risk factors of coronary artery disease in Kazakh patients, while BMI and betatrophin were the risk factors in Han patients. It suggests that we should also pay attention to ethnic differences in the study of coronary heart disease." [Collapse]

Qin L, Rehemuding R, Ainiwaer A, Ma X. Correlation between betatrophin/angiogenin-likeprotein3/lipoprotein lipase pathway and severity of coronary artery disease in Kazakh patients with coronary heart disease. World J Clin Cases 2022; 10(7): 2095-2105 [PMID: 35321188 DOI: 10.12998/wjcc.v10.i7.2095]

"I consider this manuscript is of a topic of great importance, such as pain management in critically ill patients in intensive care ..." [Read more]

"I consider this manuscript is of a topic of great importance, such as pain management in critically ill patients in intensive care units. Pain management is a process of continuous quality improvement that requires multidisciplinary team cooperation, pain-related training of all relevant personnel, effective relief of all kinds of pain, and improvement of patients' quality of life. Knowing the types of pain and risk factors will help to provide an individualized pain management based on pharmacokinetics and pharmacodynamics. " [Collapse]

Guo NN, Wang HL, Zhao MY, Li JG, Liu HT, Zhang TX, Zhang XY, Chu YJ, Yu KJ, Wang CS. Management of procedural pain in the intensive care unit. World J Clin Cases 2022; 10(5): 1473-1484 [PMID: 35211585 DOI: 10.12998/wjcc.v10.i5.1473]

"All comments are presented our in our submitted letter to the editor"

Rubin SJS, Balabanis T, Gubatan J, Habtezion A. Disease exacerbation is common in inflammatory bowel disease patients treated with immune checkpoint inhibitors for malignancy. World J Clin Cases 2022; 10(6): 1787-1794 [PMID: 35317167 DOI: 10.12998/wjcc.v10.i6.1787]

"Artificial intelligence in colorectal cancer screening in patients with inflammatory bowel disease Thank you for inviting me to ..." [Read more]

"Artificial intelligence in colorectal cancer screening in patients with inflammatory bowel disease Thank you for inviting me to comment on the above-titled manuscript. First, I congratulate the authors on their publication. However, I have a few comments and suggestions- Abstract- I suggest instead of the descriptive statements, the authors may need to address 3 points: 1) What are current tools used to detect CRC in patients with IBD early? 2) What are the main limitations of these tools? 3) How AI can help in filling the gap? The section on (AI in Gastrointestinal Endoscopy) is redundant and is away from the scope of the review. Instead, the authors should have addressed the 3 questions presented above. Thank you " [Collapse]

Marques KF, Marques AF, Lopes MA, Beraldo RF, Lima TB, Sassaki LY. Artificial intelligence in colorectal cancer screening in patients with inflammatory bowel disease. Artif Intell Gastrointest Endosc 2022; 3(1): 1-8 [DOI: 10.37126/aige.v3.i1.1]

"The manuscript is well written and dwells into details of a relatively uncommonly encountered medical diagnosis. "

Lee YJ, Kim YS. Cryptogenic organizing pneumonia associated with pregnancy: A case report. World J Clin Cases 2022; 10(6): 1946-1951 [PMID: 35317155 DOI: 10.12998/wjcc.v10.i6.1946]

"The authors do a good job of explaining the pathophysiology and diagnosis of Tubercular Pericarditis which is disease that is ..." [Read more]

"The authors do a good job of explaining the pathophysiology and diagnosis of Tubercular Pericarditis which is disease that is uncommonly encountered" [Collapse]

Lucero OD, Bustos MM, Ariza Rodríguez DJ, Perez JC. Tuberculous pericarditis-a silent and challenging disease: A case report. World J Clin Cases 2022; 10(6): 1869-1875 [PMID: 35317150 DOI: 10.12998/wjcc.v10.i6.1869]

"There are many studies on the overproduction of reactive oxygen species (ROS) in liver toxicity and chronic liver disease resulting ..." [Read more]

"There are many studies on the overproduction of reactive oxygen species (ROS) in liver toxicity and chronic liver disease resulting in oxidative stress and endoplasmic reticulum stress. The study of Silvia Bona et al., is among these. The authors have evaluated the damage induced by CCL4 administration to rats and the effect on the liver toxicity of melatonin, the hormone derives from the amino acid tryptophan and is produced by the pineal gland, with a variety of effects on mood, sleep, reproduction, immune system, circadian rhythm, aging and thus modulating antioxidant defense system. The biochemical analysis indicates that the transaminases and alkaline phosphatase were increased in CCL4 –treated animals and Melatonin was able to bring the levels of enzyme activities back to basal. Melatonin also was able to restore the peroxidation markers, LPO and SOD activity as well as the protein markers related to oxidative stress Keap1/Nrf2 pathway. An here comes the more original part of the article of Bona et al., a less common parameter, such as endoplasmic reticulum stress and the protein folding were also taken into account, measuring the markers of ER stress: ATF6 and GRP78/BiP. Redox stress impair the protein synthesis resulting in accumulation of misfolded proteins. The expression of these proteins was increased in CCL4- treated animals and melatonin was able to restore the levels to basal. Unfolded proteins are very toxic due to their capability to aggregate, therefore eukariotic cells have evolved systems able to prevent excessive accumulation of proteins in the endoplasmic reticulum that may give rise to a complex reaction called unfolded protein response (UPR). UPR in turn gives rise to an increased transcription of the specific genes leading to the synthesis of chaperones proteins of ER or they may slow down the synthesis of the new proteins, to keep it low and reduce aggregation. Other parameters very important for cellular proteins to keep low the excessive redox levels and protein folding are Heat Shock Proteins (HSP) and the nuclear Heat Shock Factor 1 (HSF1). Among heat shock proteins, a protein family most conserved in evolution expressed both constitutively and inducibly is the HSP70. Another interesting paramenter studied by Bona et al.,in addition to the biochemical parameters measured is the level of Zinc. Zinc is a very important micronutrient essential for human health starting from protein physiology and function (i.e.insulin) up to oxidative markers and its dysregulation may be an important determinant of several pathologies such as anemia, growth retardation, skin alteration , mental impairment, macular degeneration, blindness. Zinc deficiency impairs situations of oxidative stress and its markers. The zinc levels was dramatically decreased in cytotoxic hepatocytes, but melatonin restored its level to normal control value, confirming once more its efficiency, not only as an antioxidant. Melatonin is probably able to modulate zinc level and its association to circadian rhythm. To summarize, the paper of Bona et al., has a very good consistency since the authors take into account not only the known biochemical parameters, but also zinc levels, a micronutrient essential for human health, and UPR, very important to know how the membrane-bound transcription factors as well as the cell function and structure are regulated. " [Collapse]

Bona S, Fernandes SA, Moreira ACJ, Rodrigues G, Schemitt EG, Di Naso FC, Marroni CA, Marroni NP. Melatonin restores zinc levels, activates the Keap1/Nrf2 pathway, and modulates endoplasmic reticular stress and HSP in rats with chronic hepatotoxicity. World J Gastrointest Pharmacol Ther 2022; 13(2): 11-22 [DOI: 10.4292/wjgpt.v13.i2.11]

"It would have been nice to separate as three big topics: initiation, promotion, and progression. Anyhow, it is an interesting review. ..." [Read more]

"It would have been nice to separate as three big topics: initiation, promotion, and progression. Anyhow, it is an interesting review." [Collapse]

Currais P, Rosa I, Claro I. Colorectal cancer carcinogenesis: From bench to bedside. World J Gastrointest Oncol 2022; 14(3): 654-663 [PMID: 35321283 DOI: 10.4251/wjgo.v14.i3.654]

"Concise and effective letter. Shareable its content"

Okumura K. Re: Association between intestinal neoplasms and celiac disease - beyond celiac disease and more. World J Gastrointest Oncol 2022; 14(3): 746-747 [PMID: 35321274 DOI: 10.4251/wjgo.v14.i3.746]

"In my opinion, the limitation of this minireview is that the topic is treated in a too generalist way, the reader receives some ..." [Read more]

"In my opinion, the limitation of this minireview is that the topic is treated in a too generalist way, the reader receives some information that in truth is not explained in depth. Finally, the references are not quite recent, as one would expect from such an innovative topic. However, it is a minireview and this could be enough to create sufficient interest and stimulus to the reader" [Collapse]

Burati M, Tagliabue F, Lomonaco A, Chiarelli M, Zago M, Cioffi G, Cioffi U. Artificial intelligence as a future in cancer surgery. Artif Intell Cancer 2022; 3(1): 11-16 [DOI: 10.35713/aic.v3.i1.11]

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